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Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity

Patients often report: Fewer IBD flare-ups Improved digestion and nutrient absorption Reduced bloating and bowel discomfort Better daily energy and focus Improved skin clarity (from reduced systemic inflammation) Patients notice steady improvement over time as inflammation quiets and the gut lining begins to heal, says Dr

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